Membrane Remodeling

Biological membranes are far more than static barriers; they are highly dynamic, living interfaces that coordinate the intricate signaling networks of the cell. Membrane remodeling is a continuous and ubiquitous process essential for life. In a healthy cell, membranes are under constant physical and chemical transformation to facilitate essential processes, including vesicular traffic, organelle maintenance, and stress response. The "logic" of these remodeling events is often driven by specialized proteins that sense lipid identity and membrane curvature. Our lab seeks to bridge the gap between the basic mechanistic insights of membrane remodeling and their application in therapeutic intervention.