Publications

Structural basis for mTORC1 activation on the lysosomal membrane

Structural basis for mTORC1 activation on the lysosomal membrane

Zhicheng Cui, Alessandra Esposito, Gennaro Napolitano, Andrea Ballabio, James H. Hurley
Nature(2025)DOI: 10.1038/s41586-025-09545-3
Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

Zhicheng Cui, Gennaro Napolitano, Mariana E. G. de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A. Huber, Andrea Ballabio, James H. Hurley
Nature(2023)DOI: 10.1038/s41586-022-05652-7
Amino acid sensing and lysosomal signaling complexes

Amino acid sensing and lysosomal signaling complexes

Zhicheng Cui, Aaron M.N. Joiner, Rachel M. Jansen, James H. Hurley
Current Opinion in Structural Biology(2023)DOI: 10.1016/j.sbi.2023.102544
Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents

Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents

Jidong Zhang, Christine Lair, Christine Roubert, Kwame Amaning, María Belén Barrio, Yannick Benedetti, Zhicheng Cui, Zhongliang Xing, Xiaojun Li, Scott G. Franzblau, Nicolas Baurin, Florence Bordon-Pallier, Cathy Cantalloube, Stephanie Sans, Sandra Silve, Isabelle Blanc, Laurent Fraisse, Alexey Rak, Lasse B. Jenner, Gulnara Yusupova, Marat Yusupov, Junjie Zhang, Takushi Kaneko, T.J. Yang, Nader Fotouhi, Eric Nuermberger, Sandeep Tyagi, Fabrice Betoudji, Anna Upton, James C. Sacchettini, Sophie Lagrange
Cell(2023)DOI: 10.1016/j.cell.2023.01.043
Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis

Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis

Zhicheng Cui, Xiaojun Li, Joonyoung Shin, Howard Gamper, Ya-Ming Hou, James C. Sacchettini, Junjie Zhang
Nature Communications(2022)DOI: 10.1038/s41467-022-28078-1
Hierarchical natural move Monte Carlo refines flexible RNA structures into cryo-EM densities

Hierarchical natural move Monte Carlo refines flexible RNA structures into cryo-EM densities

Jeng-Yih Chang, Zhicheng Cui, Kailu Yang, Jianhua Huang, Peter Minary, Junjie Zhang
RNA(2020)DOI: 10.1261/rna.071100.119
Page 1 of 3Older →